3U7N

Crystal structures of the Staphylococcus aureus peptide deformylase in complex with two classes of new inhibitors

Summary for 3U7N

Entry DOI	10.2210/pdb3u7n/pdb
Related	3U7K 3U7L 3U7M
Descriptor	Peptide deformylase, ZINC ION, N-((2R,4S)-2-butyl-5-methyl-4-(3-(5-methylpyridin-2-yl)ureido)-3-oxohexyl)-N-hydroxyformamide, ... (4 entities in total)
Functional Keywords	pdf-inhibitor, pdf, peptide deformylase, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Staphylococcus aureus
Total number of polymer chains	1
Total formula weight	22136.59
Authors	Lee, S.J.,Lee, S.-J.,Lee, S.K.,Yoon, H.-J.,Lee, H.H.,Kim, K.K.,Lee, B.J.,Suh, S.W. (deposition date: 2011-10-14, release date: 2012-06-27, Last modification date: 2023-11-01)
Primary citation	Lee, S.J.,Lee, S.-J.,Lee, S.K.,Yoon, H.-J.,Lee, H.H.,Kim, K.K.,Lee, B.J.,Lee, B.I.,Suh, S.W. Structures of Staphylococcus aureus peptide deformylase in complex with two classes of new inhibitors Acta Crystallogr.,Sect.D, 68:784-793, 2012 Cited by PubMed: 22751663 DOI: 10.1107/S0907444912011912 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation