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3U4I

CD38 structure-based inhibitor design using the N1-cyclic inosine 5'-diphosphate ribose template

Summary for 3U4I
Entry DOI10.2210/pdb3u4i/pdb
Related3U4H
DescriptorADP-ribosyl cyclase 1, Cyclic adenosine 5'-diphosphocarbocyclic ribose (3 entities in total)
Functional Keywordsnon-hydrolyzable inhibitor, two domains, cadpr cyclization, hydrolysis, cadpcr, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceHomo sapiens (human)
Cellular locationMembrane; Single-pass type II membrane protein: P28907
Total number of polymer chains2
Total formula weight61300.11
Authors
Liu, Q.,Hao, Q.,Lee, H.C.,Graeff, R. (deposition date: 2011-10-08, release date: 2012-10-10, Last modification date: 2023-11-01)
Primary citationMoreau, C.,Liu, Q.,Graeff, R.,Wagner, G.K.,Thomas, M.P.,Swarbrick, J.M.,Shuto, S.,Lee, H.C.,Hao, Q.,Potter, B.V.L.
CD38 Structure-Based Inhibitor Design Using the N1-Cyclic Inosine 5'-Diphosphate Ribose Template
Plos One, 8:e66247-e66247, 2013
Cited by
PubMed: 23840430
DOI: 10.1371/journal.pone.0066247
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.118 Å)
Structure validation

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