3TL1
Crystal structure of the Streptomyces coelicolor WhiE ORFVI polyketide aromatase/cyclase
Summary for 3TL1
Entry DOI | 10.2210/pdb3tl1/pdb |
Descriptor | Polyketide cyclase, 6,7,9-trihydroxy-3-methyl-1H-benzo[g]isochromen-1-one, GLYCEROL, ... (4 entities in total) |
Functional Keywords | helix-grip fold, polyketide c9-c14 aromatase/cyclase, linear poly-beta-ketone intermediate, biosynthetic protein |
Biological source | Streptomyces coelicolor |
Total number of polymer chains | 2 |
Total formula weight | 37225.41 |
Authors | Lee, M.-Y.,Ames, B.D.,Zhang, W.,Tang, Y.,Tsai, S.-C. (deposition date: 2011-08-29, release date: 2012-04-04, Last modification date: 2024-02-28) |
Primary citation | Lee, M.Y.,Ames, B.D.,Tsai, S.C. Insight into the Molecular Basis of Aromatic Polyketide Cyclization: Crystal Structure and in Vitro Characterization of WhiE-ORFVI. Biochemistry, 51:3079-3091, 2012 Cited by PubMed: 22432862DOI: 10.1021/bi201705q PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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