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3TJ5

human vinculin head domain (Vh1, residues 1-258) in complex with the vinculin binding site of the surface cell antigen 4 (sca4-VBS-N; residues 412-434) from Rickettsia rickettsii

Summary for 3TJ5
Entry DOI10.2210/pdb3tj5/pdb
Related1rkc 2gww 2hsq 2ibf 3TJ6 3rf3 3s90
DescriptorVinculin, Antigenic heat-stable 120 kDa protein, GLYCEROL, ... (4 entities in total)
Functional Keywordscytoskeleton, epidemic typhus, sca4, spotted fever, alpha-helix bundle domain, protein-protein interactions, cell adhesion, cytosol, focal adhesion, protein binding-toxin complex, protein binding/toxin
Biological sourceHomo sapiens (human)
More
Cellular locationCell membrane ; Peripheral membrane protein ; Cytoplasmic side : P18206
Total number of polymer chains2
Total formula weight31469.28
Authors
Park, H.,Lee, J.H.,Gouin, E.,Cossart, P.,Izard, T. (deposition date: 2011-08-23, release date: 2011-09-07, Last modification date: 2023-09-13)
Primary citationPark, H.,Lee, J.H.,Gouin, E.,Cossart, P.,Izard, T.
The rickettsia surface cell antigen 4 applies mimicry to bind to and activate vinculin.
J.Biol.Chem., 286:35096-35103, 2011
Cited by
PubMed: 21841197
DOI: 10.1074/jbc.M111.263855
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.99 Å)
Structure validation

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