3T3J

1.70 A structure of Friedreich's ataxia frataxin variant N146K

Summary for 3T3J

Entry DOI	10.2210/pdb3t3j/pdb
Related	3T3K 3T3L 3T3T 3T3X
Descriptor	Frataxin, mitochondrial (2 entities in total)
Functional Keywords	fe-s cluster biosynthesis, human mitochondria, oxidoreductase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: Q16595
Total number of polymer chains	1
Total formula weight	14210.73
Authors	Bridwell-Rabb, J.,Winn, A.M.,Barondeau, D.P. (deposition date: 2011-07-25, release date: 2011-08-10, Last modification date: 2024-02-28)
Primary citation	Bridwell-Rabb, J.,Winn, A.M.,Barondeau, D.P. Structure-Function Analysis of Friedreich's Ataxia Mutants Reveals Determinants of Frataxin Binding and Activation of the Fe-S Assembly Complex. Biochemistry, 50:7265-7274, 2011 Cited by PubMed: 21776984 DOI: 10.1021/bi200895k PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation