3SMQ
Crystal structure of protein arginine methyltransferase 3
Summary for 3SMQ
Entry DOI | 10.2210/pdb3smq/pdb |
Descriptor | Protein arginine N-methyltransferase 3, 1-(1,2,3-benzothiadiazol-6-yl)-3-[2-(cyclohex-1-en-1-yl)ethyl]urea, CHLORIDE ION, ... (5 entities in total) |
Functional Keywords | structural genomics, structural genomics consortium, sgc, prmt3, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: O60678 |
Total number of polymer chains | 1 |
Total formula weight | 38619.76 |
Authors | Dobrovetsky, E.,Dong, A.,Walker, J.R.,Siarheyeva, A.,Senisterra, G.,Wasney, G.A.,Smil, D.,Bolshan, Y.,Nguyen, K.T.,Allali-Hassani, A.,Hajian, T.,Poda, G.,Bountra, C.,Weigelt, J.,Edwards, A.M.,Al-Awar, R.,Brown, P.J.,Schapira, M.,Arrowsmith, C.H.,Vedadi, M.,Structural Genomics Consortium (SGC) (deposition date: 2011-06-28, release date: 2011-08-31, Last modification date: 2023-09-13) |
Primary citation | Siarheyeva, A.,Senisterra, G.,Allali-Hassani, A.,Dong, A.,Dobrovetsky, E.,Wasney, G.A.,Chau, I.,Marcellus, R.,Hajian, T.,Liu, F.,Korboukh, I.,Smil, D.,Bolshan, Y.,Min, J.,Wu, H.,Zeng, H.,Loppnau, P.,Poda, G.,Griffin, C.,Aman, A.,Brown, P.J.,Jin, J.,Al-Awar, R.,Arrowsmith, C.H.,Schapira, M.,Vedadi, M. An allosteric inhibitor of protein arginine methyltransferase 3. Structure, 20:1425-1435, 2012 Cited by PubMed: 22795084DOI: 10.1016/j.str.2012.06.001 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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