3SMQ

Crystal structure of protein arginine methyltransferase 3

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Protein arginine N-methyltransferase 3	polymer	340	38281.9	1	UniProt (O60678) Pfam (PF06325) Pfam (PF22528) In PDB	Homo sapiens (human)	Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3
2	A	1-(1,2,3-benzothiadiazol-6-yl)-3-[2-(cyclohex-1-en-1-yl)ethyl]urea	non-polymer		302.4	1	Chemie (TDU)
3	A	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
4	A	UNKNOWN ATOM OR ION	non-polymer			10	Chemie (UNX)
5		water	water		18.0	223	Chemie (HOH)

Sequence modifications

A: 228 - 548 (UniProt: O60678)

PDB	External Database	Details
Met 209	-	expression tag
Gly 210	-	expression tag
Ser 211	-	expression tag
Ser 212	-	expression tag
His 213	-	expression tag
His 214	-	expression tag
His 215	-	expression tag
His 216	-	expression tag
His 217	-	expression tag
His 218	-	expression tag
Ser 219	-	expression tag
Ser 220	-	expression tag
Gly 221	-	expression tag
Leu 222	-	expression tag
Val 223	-	expression tag
Pro 224	-	expression tag
Arg 225	-	expression tag
Gly 226	-	expression tag
Ser 227	-	expression tag
Asn 525	Ser 508	variant

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	38281.9
Non-Polymers*	Number of molecules	12
	Total formula weight	337.8
All*	Total formula weight	38619.8

*Water molecules are not included.