3SKJ

Structural And Functional Characterization of an Agonistic Anti-Human EphA2 Monoclonal Antibody

Summary for 3SKJ

• Entry DOI: 10.2210/pdb3skj/pdb
• Descriptor: Antibody, light chain, Antibody, heavy chain, Ephrin type-A receptor 2, ... (4 entities in total)
• Functional Keywords: fab, receptor, ig fold, ephrin receptor, antibody, antigen, extra-cellular, immune system
• Biological source: Homo sapiens (human); More
• Cellular location: Cell membrane ; Single- pass type I membrane protein : P29317
• Total number of polymer chains: 6
• Total formula weight: 142941.75

Authors

Oganesyan, V.Y.,Wu, H.,Dall'Acqua, W.F. (deposition date: 2011-06-22, release date: 2011-08-31, Last modification date: 2017-05-31)

• Primary citation: Peng, L.,Oganesyan, V.,Damschroder, M.M.,Wu, H.,Dall'Acqua, W.F.; Structural and functional characterization of an agonistic anti-human EphA2 monoclonal antibody.; J.Mol.Biol., 413:390-405, 2011; PubMed: 21867711; DOI: 10.1016/j.jmb.2011.08.018

Experimental method

X-RAY DIFFRACTION (2.5 Å)