3SKJ
Structural And Functional Characterization of an Agonistic Anti-Human EphA2 Monoclonal Antibody
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | L, M | Antibody, light chain | polymer | 214 | 23482.1 | 2 | Homo sapiens (human) | ||
2 | H, I | Antibody, heavy chain | polymer | 231 | 24420.3 | 2 | Homo sapiens (human) | ||
3 | E, F | Ephrin type-A receptor 2 | polymer | 206 | 23568.5 | 2 | UniProt (P29317) Pfam (PF01404) In PDB | Homo sapiens (Human) | Epithelial cell kinase,Tyrosine-protein kinase receptor ECK |
4 | water | water | 18.0 | 43 | Chemie (HOH) |
Sequence modifications
E, F: -1 - 178 (UniProt: P29317)
PDB | External Database | Details |
---|---|---|
Ala -27 | - | expression tag |
Pro -26 | - | expression tag |
Glu -25 | - | expression tag |
His -24 | - | expression tag |
His -23 | - | expression tag |
His -22 | - | expression tag |
His -21 | - | expression tag |
His -20 | - | expression tag |
His -19 | - | expression tag |
Asp -18 | - | expression tag |
Tyr -17 | - | expression tag |
Asp -16 | - | expression tag |
Ile -15 | - | expression tag |
Pro -14 | - | expression tag |
Thr -13 | - | expression tag |
Thr -12 | - | expression tag |
Glu -11 | - | expression tag |
Asn -10 | - | expression tag |
Leu -9 | - | expression tag |
Tyr -8 | - | expression tag |
Phe -7 | - | expression tag |
Gln -6 | - | expression tag |
Gly -5 | - | expression tag |
Ala -4 | - | expression tag |
Met -3 | - | expression tag |
Asp -2 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 142941.7 | |
All* | Total formula weight | 142941.7 |