3S5Y
Pharmacological Chaperoning in Human alpha-Galactosidase
Summary for 3S5Y
Entry DOI | 10.2210/pdb3s5y/pdb |
Related | 1R46 1R47 3HG2 3HG3 3HG4 3HG5 3S5Z |
Descriptor | Alpha-galactosidase A, 1,2-ETHANEDIOL, ACETIC ACID, ... (12 entities in total) |
Functional Keywords | glycoprotein, carbohydrate-binding protein, glycosidase, lysosomal enzyme, (beta/alpha)8 barrel, pharmacological chaperone, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 97829.15 |
Authors | Guce, A.I.,Clark, N.E.,Garman, S.C. (deposition date: 2011-05-23, release date: 2012-01-04, Last modification date: 2023-09-13) |
Primary citation | Guce, A.I.,Clark, N.E.,Rogich, J.J.,Garman, S.C. The molecular basis of pharmacological chaperoning in human alpha-galactosidase Chem.Biol., 18:1521-1526, 2011 Cited by PubMed: 22195554DOI: 10.1016/j.chembiol.2011.10.012 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.105 Å) |
Structure validation
Download full validation report