3S4S
Crystal structure of CD4 mutant bound to HLA-DR1
Summary for 3S4S
Entry DOI | 10.2210/pdb3s4s/pdb |
Related | 3S5L |
Descriptor | HLA class II histocompatibility antigen, DR alpha chain, HLA class II histocompatibility antigen, DRB1-1 beta chain, Hemagglutinin peptide, ... (6 entities in total) |
Functional Keywords | protein-protein complex, immune system |
Biological source | Homo sapiens (human) More |
Cellular location | Cell membrane; Single-pass type I membrane protein: P01903 P04229 P01730 |
Total number of polymer chains | 8 |
Total formula weight | 133014.05 |
Authors | |
Primary citation | Wang, X.X.,Li, Y.,Yin, Y.,Mo, M.,Wang, Q.,Gao, W.,Wang, L.,Mariuzza, R.A. Affinity maturation of human CD4 by yeast surface display and crystal structure of a CD4-HLA-DR1 complex. Proc.Natl.Acad.Sci.USA, 108:15960-15965, 2011 Cited by PubMed: 21900604DOI: 10.1073/pnas.1109438108 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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