3RO5
Crystal structure of influenza A virus nucleoprotein with ligand
Summary for 3RO5
Entry DOI | 10.2210/pdb3ro5/pdb |
Descriptor | Nucleocapsid protein, [4-(2-chloro-4-nitrophenyl)piperazin-1-yl][3-(2-methoxyphenyl)-5-methyl-1,2-oxazol-4-yl]methanone (3 entities in total) |
Functional Keywords | influenza nucleoprotein, viral protein |
Biological source | Influenza A virus |
Total number of polymer chains | 2 |
Total formula weight | 114525.85 |
Authors | Pearce, B.C.,Edavettal, S.,McDonnell, P.A.,Lewis, H.A.,Steinbacher, S.,Baldwin, E.T.,Langley, D.R.,Maskos, K.,Mortl, M.,Kiefersauer, R. (deposition date: 2011-04-25, release date: 2011-09-14, Last modification date: 2024-02-28) |
Primary citation | Gerritz, S.W.,Cianci, C.,Kim, S.,Pearce, B.C.,Deminie, C.,Discotto, L.,McAuliffe, B.,Minassian, B.F.,Shi, S.,Zhu, S.,Zhai, W.,Pendri, A.,Li, G.,Poss, M.A.,Edavettal, S.,McDonnell, P.A.,Lewis, H.A.,Maskos, K.,Mortl, M.,Kiefersauer, R.,Steinbacher, S.,Baldwin, E.T.,Metzler, W.,Bryson, J.,Healy, M.D.,Philip, T.,Zoeckler, M.,Schartman, R.,Sinz, M.,Leyva-Grado, V.H.,Hoffmann, H.H.,Langley, D.R.,Meanwell, N.A.,Krystal, M. Inhibition of influenza virus replication via small molecules that induce the formation of higher-order nucleoprotein oligomers. Proc.Natl.Acad.Sci.USA, 108:15366-15371, 2011 Cited by PubMed: 21896751DOI: 10.1073/pnas.1107906108 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.66 Å) |
Structure validation
Download full validation report