3QNL

Crystal structure of PrTX-I complexed to Rosmarinic Acid

Summary for 3QNL

• Entry DOI: 10.2210/pdb3qnl/pdb
• Related: 1PA0 1QLL 1XXS 1Y4L 2OK9 2Q2J 3CXI 3CYL 3I3H
• Descriptor: Phospholipase A2 homolog 1, ISOPROPYL ALCOHOL, (2R)-3-(3,4-dihydroxyphenyl)-2-{[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy}propanoic acid, ... (5 entities in total)
• Functional Keywords: hydrolase
• Biological source: Bothrops pirajai (Piraja's lance head)
• Cellular location: Secreted: P58399
• Total number of polymer chains: 2
• Total formula weight: 28675.66

Authors

dos Santos, J.I.,Fontes, M.R.M. (deposition date: 2011-02-08, release date: 2012-02-29, Last modification date: 2023-12-27)

• Primary citation: Dos Santos, J.I.,Cardoso, F.F.,Soares, A.M.,Dal Pai Silva, M.,Gallacci, M.,Fontes, M.R.; Structural and Functional Studies of a Bothropic Myotoxin Complexed to Rosmarinic Acid: New Insights into Lys49-PLA(2) Inhibition.; Plos One, 6:e28521-e28521, 2011; PubMed: 22205953; DOI: 10.1371/journal.pone.0028521

Experimental method

X-RAY DIFFRACTION (1.77 Å)