Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004623 | molecular_function | phospholipase A2 activity |
| A | 0005509 | molecular_function | calcium ion binding |
| A | 0005543 | molecular_function | phospholipid binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0006644 | biological_process | phospholipid metabolic process |
| A | 0016042 | biological_process | lipid catabolic process |
| A | 0035821 | biological_process | modulation of process of another organism |
| A | 0042130 | biological_process | negative regulation of T cell proliferation |
| A | 0050482 | biological_process | arachidonate secretion |
| A | 0090729 | molecular_function | toxin activity |
| B | 0004623 | molecular_function | phospholipase A2 activity |
| B | 0005509 | molecular_function | calcium ion binding |
| B | 0005543 | molecular_function | phospholipid binding |
| B | 0005576 | cellular_component | extracellular region |
| B | 0006644 | biological_process | phospholipid metabolic process |
| B | 0016042 | biological_process | lipid catabolic process |
| B | 0035821 | biological_process | modulation of process of another organism |
| B | 0042130 | biological_process | negative regulation of T cell proliferation |
| B | 0050482 | biological_process | arachidonate secretion |
| B | 0090729 | molecular_function | toxin activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE IPA A 201 |
| Chain | Residue |
| A | TYR22 |
| A | CYS29 |
| A | GLY30 |
| A | IPA202 |
| A | HOH381 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE IPA A 202 |
| Chain | Residue |
| A | IPA201 |
| A | HOH410 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE IPA A 203 |
| Chain | Residue |
| A | HOH411 |
| A | LYS115 |
| A | ARG118 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE IPA A 204 |
| Chain | Residue |
| A | ASN87 |
| A | ASN88 |
| A | GLU108 |
| A | HOH394 |
| B | IPA203 |
| site_id | AC5 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE ROA A 205 |
| Chain | Residue |
| A | PHE3 |
| A | LYS7 |
| A | LEU10 |
| A | GLN11 |
| A | GLY15 |
| A | HOH395 |
| A | HOH399 |
| A | HOH426 |
| A | HOH427 |
| B | LYS7 |
| B | LEU10 |
| B | GLN11 |
| B | TRP77 |
| B | P33205 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE IPA B 201 |
| Chain | Residue |
| B | CYS29 |
| B | GLY30 |
| B | P33205 |
| B | HOH386 |
| site_id | AC7 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE IPA B 202 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE IPA B 203 |
| Chain | Residue |
| A | IPA204 |
| A | HOH379 |
| B | LYS53 |
| B | LYS57 |
| B | HOH361 |
| B | HOH381 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE IPA B 204 |
| Chain | Residue |
| B | LYS36 |
| B | PRO37 |
| B | LYS38 |
| site_id | BC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE P33 B 205 |
| Chain | Residue |
| A | LEU10 |
| A | PRO123 |
| A | ROA205 |
| B | LEU2 |
| B | LEU121 |
| B | IPA201 |
Functional Information from PROSITE/UniProt
| site_id | PS00118 |
| Number of Residues | 8 |
| Details | PA2_HIS Phospholipase A2 histidine active site. CCYvHKcC |
| Chain | Residue | Details |
| A | CYS44-CYS51 | |
| site_id | PS00119 |
| Number of Residues | 11 |
| Details | PA2_ASP Phospholipase A2 aspartic acid active site. LCECDKAVaIC |
| Chain | Residue | Details |
| A | LEU95-CYS105 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 24 |
| Details | Region: {"description":"Important for membrane-damaging activities in eukaryotes and bacteria; heparin-binding","evidences":[{"source":"UniProtKB","id":"P24605","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Site: {"description":"Important residue of the cationic membrane-docking site (MDoS)","evidences":[{"source":"UniProtKB","id":"I6L8L6","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Site: {"description":"Hydrophobic membrane-disruption site (MDiS)","evidences":[{"source":"UniProtKB","id":"I6L8L6","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Site: {"description":"Cationic membrane-docking site (MDoS)","evidences":[{"source":"UniProtKB","id":"I6L8L6","evidenceCode":"ECO:0000250"}]} |
