3QFB

Crystal structure of the human thioredoxin reductase-thioredoxin complex

Summary for 3QFB

Entry DOI	10.2210/pdb3qfb/pdb
Related	3QFA
Descriptor	Thioredoxin reductase 1, cytoplasmic, Thioredoxin, FLAVIN-ADENINE DINUCLEOTIDE, ... (5 entities in total)
Functional Keywords	protein-protein complex, rossmann fold, thioredoxin fold, homodimeric pyridine nucleotide disulfide oxidoreductase, electron transport, oxidoreductase
Biological source	Homo sapiens (human) More
Cellular location	Cytoplasm (By similarity). Isoform 4: Cytoplasm. Isoform 5: Cytoplasm: Q16881 Nucleus: P10599
Total number of polymer chains	4
Total formula weight	141960.64
Authors	Fritz-Wolf, K.,Kehr, S.,Stumpf, M.,Rahlfs, S.,Becker, K. (deposition date: 2011-01-21, release date: 2011-07-27, Last modification date: 2023-11-01)
Primary citation	Fritz-Wolf, K.,Kehr, S.,Stumpf, M.,Rahlfs, S.,Becker, K. Crystal structure of the human thioredoxin reductase-thioredoxin complex Nat Commun, 2:383-383, 2011 Cited by PubMed: 21750537 DOI: 10.1038/ncomms1382 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation