3QAM

Crystal Structure of Glu208Ala mutant of catalytic subunit of cAMP-dependent protein kinase

Summary for 3QAM

• Entry DOI: 10.2210/pdb3qam/pdb
• Related: 1ATP 3QAL
• Descriptor: cAMP-dependent protein kinase catalytic subunit alpha, Protein kinase inhibitor, ADENOSINE-5'-TRIPHOSPHATE, ... (5 entities in total)
• Functional Keywords: glu208/arg280 pair;, catalytic subunit, pka, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Mus musculus (mouse)
• Cellular location: Cytoplasm: P05132
• Total number of polymer chains: 2
• Total formula weight: 43266.40

Authors

Yang, J.,Wu, J.,Steichen, J.,Taylor, S.S. (deposition date: 2011-01-11, release date: 2011-12-07, Last modification date: 2023-09-13)

• Primary citation: Yang, J.,Wu, J.,Steichen, J.M.,Kornev, A.P.,Deal, M.S.,Li, S.,Sankaran, B.,Woods, V.L.,Taylor, S.S.; A conserved Glu-Arg salt bridge connects coevolved motifs that define the eukaryotic protein kinase fold.; J.Mol.Biol., 415:666-679, 2012; PubMed: 22138346; DOI: 10.1016/j.jmb.2011.11.035

Experimental method

X-RAY DIFFRACTION (1.92 Å)