3PL1
Determination of the crystal structure of the pyrazinamidase from M.tuberculosis : a structure-function analysis for prediction resistance to pyrazinamide.
Replaces: 3GBCSummary for 3PL1
| Entry DOI | 10.2210/pdb3pl1/pdb |
| Descriptor | PYRAZINAMIDASE/NICOTINAMIDASE PNCA (PZase), FE (II) ION (3 entities in total) |
| Functional Keywords | rossmann fold, nicotinamidase-pyrazinamidase, resistance to pyrazinamide, hydrolase |
| Biological source | Mycobacterium tuberculosis |
| Total number of polymer chains | 1 |
| Total formula weight | 19677.42 |
| Authors | Petrella, S.,Gelus-Ziental, N.,Mayer, C.,Sougakoff, W. (deposition date: 2010-11-12, release date: 2011-01-12, Last modification date: 2023-11-01) |
| Primary citation | Petrella, S.,Gelus-Ziental, N.,Maudry, A.,Laurans, C.,Boudjelloul, R.,Sougakoff, W. Crystal Structure of the Pyrazinamidase of Mycobacterium tuberculosis: Insights into Natural and Acquired Resistance to Pyrazinamide. Plos One, 6:e15785-e15785, 2011 Cited by PubMed: 21283666DOI: 10.1371/journal.pone.0015785 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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