3P3G
Crystal Structure of the Escherichia coli LpxC/LPC-009 complex
Summary for 3P3G
Entry DOI | 10.2210/pdb3p3g/pdb |
Related | 3P3C 3P3E 3P3G |
Descriptor | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase, ZINC ION, N-[(1S,2R)-2-hydroxy-1-(hydroxycarbamoyl)propyl]-4-(4-phenylbuta-1,3-diyn-1-yl)benzamide, ... (7 entities in total) |
Functional Keywords | lipid a biosynthesis, lipid a synthesis, lpxc, baab sandwich, hydrolase, deacetylation, antibiotic, acyl udp-glcnac, hydroxamate, lpc-009 |
Biological source | Escherichia coli |
Total number of polymer chains | 1 |
Total formula weight | 34800.83 |
Authors | Lee, C.-J.,Zhou, P. (deposition date: 2010-10-04, release date: 2011-01-05, Last modification date: 2024-02-21) |
Primary citation | Lee, C.J.,Liang, X.,Chen, X.,Zeng, D.,Joo, S.H.,Chung, H.S.,Barb, A.W.,Swanson, S.M.,Nicholas, R.A.,Li, Y.,Toone, E.J.,Raetz, C.R.,Zhou, P. Species-specific and inhibitor-dependent conformations of LpxC: implications for antibiotic design. Chem.Biol., 18:38-47, 2011 Cited by PubMed: 21167751DOI: 10.1016/j.chembiol.2010.11.011 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.65 Å) |
Structure validation
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