3OXQ

Crystal Structure of Ca2+/CaM-CaV1.2 pre-IQ/IQ domain complex

Summary for 3OXQ

Entry DOI	10.2210/pdb3oxq/pdb
Descriptor	Calmodulin, Voltage-dependent L-type calcium channel subunit alpha-1C, CALCIUM ION, ... (4 entities in total)
Functional Keywords	ef hand iq domain, calcium sensing, calcium binding, ion channel, metal binding protein-transport protein complex, metal binding protein/transport protein
Biological source	Homo sapiens (human) More
Cellular location	Cytoplasm, cytoskeleton, spindle: P62158 Membrane; Multi-pass membrane protein: Q13936
Total number of polymer chains	6
Total formula weight	86234.65
Authors	Kim, E.Y.,Rumpf, C.H.,Van Petegem, F.,Arant, R.,Findeisen, F.,Cooley, E.S.,Isacoff, E.Y.,Minor, D.L. (deposition date: 2010-09-21, release date: 2010-11-03, Last modification date: 2023-09-06)
Primary citation	Kim, E.Y.,Rumpf, C.H.,Van Petegem, F.,Arant, R.J.,Findeisen, F.,Cooley, E.S.,Isacoff, E.Y.,Minor, D.L. Multiple C-terminal tail Ca(2+)/CaMs regulate Ca(V)1.2 function but do not mediate channel dimerization. Embo J., 29:3924-3938, 2010 Cited by PubMed: 20953164 DOI: 10.1038/emboj.2010.260 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.55 Å)

Structure validation