3O2X
MMP-13 in complex with selective tetrazole core inhibitor
Summary for 3O2X
Entry DOI | 10.2210/pdb3o2x/pdb |
Related | 3KRY |
Descriptor | Collagenase 3, N-hydroxy-1-(2-methoxyethyl)-4-{[4-(3-{5-[4-(trifluoromethoxy)phenyl]-2H-tetrazol-2-yl}propoxy)phenyl]sulfonyl}piperidine-4-carboxamide, ZINC ION, ... (7 entities in total) |
Functional Keywords | hydrolase |
Biological source | Homo sapiens (human) |
Cellular location | Secreted, extracellular space, extracellular matrix (Probable): P45452 |
Total number of polymer chains | 4 |
Total formula weight | 78374.00 |
Authors | Kiefer, J.R.,Barta, T.E.,Becker, D.P.,Mathis, K.J.,Williams, J. (deposition date: 2010-07-22, release date: 2011-08-10, Last modification date: 2024-02-21) |
Primary citation | Barta, T.E.,Becker, D.P.,Bedell, L.J.,Hockerman, S.L.,Kiefer, J.R.,Li, M.H.,Villamill, C.I.,Rico, J.G.,Mcdonald, J.J. MMP-13 in complex with selective tetrazole core inhibitor To be Published, |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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