3NUM
Substrate induced remodeling of the active site regulates HtrA1 activity
Summary for 3NUM
| Entry DOI | 10.2210/pdb3num/pdb |
| Related | 3NWU |
| Descriptor | Serine protease HTRA1 (1 entity in total) |
| Functional Keywords | serine protease, degp, htra, protease, hydrolase |
| Biological source | Homo sapiens (human) |
| Cellular location | Secreted: Q92743 |
| Total number of polymer chains | 1 |
| Total formula weight | 36425.63 |
| Authors | Truebestein, L.,Tennstaedt, A.,Hauske, P.,Krojer, T.,Kaiser, M.,Clausen, T.,Ehrmann, M. (deposition date: 2010-07-07, release date: 2011-02-23, Last modification date: 2023-09-06) |
| Primary citation | Truebestein, L.,Tennstaedt, A.,Monig, T.,Krojer, T.,Canellas, F.,Kaiser, M.,Clausen, T.,Ehrmann, M. Substrate-induced remodeling of the active site regulates human HTRA1 activity. Nat.Struct.Mol.Biol., 18:386-388, 2011 Cited by PubMed: 21297635DOI: 10.1038/nsmb.2013 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.75 Å) |
Structure validation
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