3UD6
Structural analyses of covalent enzyme-substrate analogue complexes reveal strengths and limitations of de novo enzyme design
Replaces: 3NL8Summary for 3UD6
Entry DOI | 10.2210/pdb3ud6/pdb |
Related | 3NXF 3O6Y |
Descriptor | RETRO-ALDOLASE, 1-(6-METHOXYNAPHTHALEN-2-YL)BUTANE-1,3-DIONE, SULFATE ION, ... (4 entities in total) |
Functional Keywords | computationally designed, retroaldolase, tim barrel, lyase-lyase inhibitor complex, lyase/lyase inhibitor |
Biological source | ARTIFICIAL GENE |
Total number of polymer chains | 1 |
Total formula weight | 30170.66 |
Authors | Baker, D.,Stoddard, B.L.,Althoff, E.A.,Wang, L.,Jiang, L.,Moody, J.,Bolduc, J.,Lassila, J.,Hilvert, D. (deposition date: 2011-10-27, release date: 2011-11-23, Last modification date: 2023-09-13) |
Primary citation | Wang, L.,Althoff, E.A.,Bolduc, J.,Jiang, L.,Moody, J.,Lassila, J.K.,Giger, L.,Hilvert, D.,Stoddard, B.,Baker, D. Structural analyses of covalent enzyme-substrate analog complexes reveal strengths and limitations of de novo enzyme design. J.Mol.Biol., 415:615-625, 2012 Cited by PubMed: 22075445DOI: 10.1016/j.jmb.2011.10.043 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.091 Å) |
Structure validation
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