3NH7
Crystal structure of the neutralizing Fab fragment AbD1556 bound to the BMP type I receptor IA
Summary for 3NH7
Entry DOI | 10.2210/pdb3nh7/pdb |
Related | 1REW 2K3G |
Descriptor | Antibody fragment Fab AbD1556, heavy chain, Antibody fragment Fab AbD1556, light chain, Bone morphogenetic protein receptor type-1A, ... (4 entities in total) |
Functional Keywords | antibody-antigen complex, bmp receptor extracellular domain, bone morphogenetic protein, immune system |
Biological source | Homo sapiens (human) More |
Cellular location | Membrane; Single-pass type I membrane protein: P36894 |
Total number of polymer chains | 12 |
Total formula weight | 247366.70 |
Authors | Mueller, T.D.,Harth, S.,Sebald, W. (deposition date: 2010-06-14, release date: 2010-10-27, Last modification date: 2023-11-01) |
Primary citation | Harth, S.,Kotzsch, A.,Hu, J.,Sebald, W.,Mueller, T.D. A selection fit mechanism in BMP receptor IA as a possible source for BMP ligand-receptor promiscuity Plos One, 5:e13049-e13049, 2010 Cited by PubMed: 20927405DOI: 10.1371/journal.pone.0013049 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
Download full validation report