3NGO

Crystal structure of the human CNOT6L nuclease domain in complex with poly(A) DNA

Summary for 3NGO

• Entry DOI: 10.2210/pdb3ngo/pdb
• Related: 3NGN 3NGQ
• Descriptor: CCR4-NOT transcription complex subunit 6-like, 5'-D(*AP*AP*AP*A)-3', MAGNESIUM ION, ... (4 entities in total)
• Functional Keywords: protein-ssdna complex, hydrolase-dna complex, hydrolase/dna
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: Q96LI5
• Total number of polymer chains: 2
• Total formula weight: 46396.98

Authors

Wang, H.,Morita, M.,Yang, W.,Bartlam, M.,Yamamoto, T.,Rao, Z. (deposition date: 2010-06-12, release date: 2010-07-28, Last modification date: 2024-03-20)

• Primary citation: Wang, H.,Morita, M.,Yang, X.,Suzuki, T.,Yang, W.,Wang, J.,Ito, K.,Wang, Q.,Zhao, C.,Bartlam, M.,Yamamoto, T.,Rao, Z.; Crystal structure of the human CNOT6L nuclease domain reveals strict poly(A) substrate specificity.; Embo J., 2010; PubMed: 20628353; DOI: 10.1038/emboj.2010.152

Experimental method

X-RAY DIFFRACTION (2.2 Å)