3NFL
Crystal structure of the PTPN4 PDZ domain complexed with the C-terminus of the GluN2A NMDA receptor subunit
Summary for 3NFL
Entry DOI | 10.2210/pdb3nfl/pdb |
Related | 2CS5 2VPH 3NFK |
Descriptor | Tyrosine-protein phosphatase non-receptor type 4, Glutamate [NMDA] receptor subunit epsilon-1 (3 entities in total) |
Functional Keywords | pdz-pdz-binding site complex, protein binding |
Biological source | Homo sapiens (human) More |
Cellular location | Cell membrane; Peripheral membrane protein; Cytoplasmic side (By similarity): P29074 Cell membrane; Multi-pass membrane protein: Q12879 |
Total number of polymer chains | 8 |
Total formula weight | 54430.27 |
Authors | Babault, N.,Cordier, F.,Lafage, M.,Cockburn, J.,Haouz, A.,Rey, F.A.,Delepierre, M.,Buc, H.,Lafon, M.,Wolff, N. (deposition date: 2010-06-10, release date: 2011-08-24, Last modification date: 2023-09-06) |
Primary citation | Babault, N.,Cordier, F.,Lafage, M.,Cockburn, J.,Haouz, A.,Prehaud, C.,Rey, F.A.,Delepierre, M.,Buc, H.,Lafon, M.,Wolff, N. Peptides Targeting the PDZ Domain of PTPN4 Are Efficient Inducers of Glioblastoma Cell Death. Structure, 19:1518-1524, 2011 Cited by PubMed: 22000519DOI: 10.1016/j.str.2011.07.007 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.91 Å) |
Structure validation
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