3NFK

Crystal structure of the PTPN4 PDZ domain complexed with the C-terminus of a rabies virus G protein

Summary for 3NFK

Entry DOI	10.2210/pdb3nfk/pdb
Related	2CS5 2VPH 3NFL
Descriptor	Tyrosine-protein phosphatase non-receptor type 4, Glycoprotein G, GLYCEROL, ... (4 entities in total)
Functional Keywords	pdz-pdz-binding site complex, protein binding
Biological source	Homo sapiens (human) More
Cellular location	Cell membrane; Peripheral membrane protein; Cytoplasmic side (By similarity): P29074 Virion membrane; Single-pass type I membrane protein (Potential): P03524
Total number of polymer chains	4
Total formula weight	26526.06
Authors	Babault, N.,Cordier, F.,Lafage, M.,Cockburn, J.,Haouz, A.,Rey, F.A.,Delepierre, M.,Buc, H.,Lafon, M.,Wolff, N. (deposition date: 2010-06-10, release date: 2011-08-24, Last modification date: 2023-09-06)
Primary citation	Babault, N.,Cordier, F.,Lafage, M.,Cockburn, J.,Haouz, A.,Prehaud, C.,Rey, F.A.,Delepierre, M.,Buc, H.,Lafon, M.,Wolff, N. Peptides Targeting the PDZ Domain of PTPN4 Are Efficient Inducers of Glioblastoma Cell Death. Structure, 19:1518-1524, 2011 Cited by PubMed: 22000519 DOI: 10.1016/j.str.2011.07.007 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.43 Å)

Structure validation