3NCL
Crystal Structure of MT-SP1 bound to Benzamidine Phosphonate Inhibitor
Summary for 3NCL
Entry DOI | 10.2210/pdb3ncl/pdb |
Descriptor | Suppressor of tumorigenicity 14 protein, phenyl (4-carbamimidoylbenzyl)phosphonate, FORMIC ACID, ... (4 entities in total) |
Functional Keywords | proteinase-inhibitor complex, serine proteinase, benzamidine, phosphonate, serine endopeptidases, hydrolase |
Biological source | Homo sapiens (human) |
Cellular location | Membrane ; Single-pass type II membrane protein : Q9Y5Y6 |
Total number of polymer chains | 1 |
Total formula weight | 26876.02 |
Authors | |
Primary citation | Brown, C.M.,Ray, M.,Eroy-Reveles, A.A.,Egea, P.,Tajon, C.,Craik, C.S. Peptide length and leaving-group sterics influence potency of Peptide phosphonate protease inhibitors. Chem.Biol., 18:48-57, 2011 Cited by PubMed: 21276938DOI: 10.1016/j.chembiol.2010.11.007 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.19 Å) |
Structure validation
Download full validation report