3NCL
Crystal Structure of MT-SP1 bound to Benzamidine Phosphonate Inhibitor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Suppressor of tumorigenicity 14 protein | polymer | 241 | 26447.7 | 1 | UniProt (Q9Y5Y6) Pfam (PF00089) In PDB | Homo sapiens (human) | Serine protease 14, Matriptase, Membrane-type serine protease 1, MT-SP1, Prostamin, Serine protease TADG-15, Tumor-associated differentially-expressed gene 15 protein |
2 | A | phenyl (4-carbamimidoylbenzyl)phosphonate | non-polymer | 290.3 | 1 | Chemie (CCZ) | |||
3 | A | FORMIC ACID | non-polymer | 46.0 | 3 | Chemie (FMT) | |||
4 | water | water | 18.0 | 398 | Chemie (HOH) |
Sequence modifications
A: 11 - 258 (UniProt: Q9Y5Y6)
PDB | External Database | Details |
---|---|---|
Ser 127 | Cys 731 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 26447.7 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 428.3 | |
All* | Total formula weight | 26876.0 |