3MZT

Protein-induced photophysical changes to the amyloid indicator dye, thioflavin T

Summary for 3MZT

Entry DOI	10.2210/pdb3mzt/pdb
Related	3CIQ 3MYZ
Descriptor	Beta-2-microglobulin, COPPER (II) ION, 2-[4-(dimethylamino)phenyl]-3,6-dimethyl-1,3-benzothiazol-3-ium, ... (4 entities in total)
Functional Keywords	thioflavin t, amyloid, parkinson's, alzheimer's, immune system
Biological source	Homo sapiens (human)
Cellular location	Secreted . Note=(Microbial infection) In the presence of M: P61769
Total number of polymer chains	6
Total formula weight	72561.81
Authors	Wolfe, L.S.,Calabrese, M.F.,Nath, A.,Blaho, D.V.,Miranker, A.D.,Xiong, Y. (deposition date: 2010-05-13, release date: 2010-09-08, Last modification date: 2023-09-06)
Primary citation	Wolfe, L.S.,Calabrese, M.F.,Nath, A.,Blaho, D.V.,Miranker, A.D.,Xiong, Y. Protein-induced photophysical changes to the amyloid indicator dye thioflavin T. Proc.Natl.Acad.Sci.USA, 107:16863-16868, 2010 Cited by PubMed: 20826442 DOI: 10.1073/pnas.1002867107 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation