3MNU
Carbonic anhydrase inhibitors: crystallographic and solution binding studies for the interaction of a boron containing aromatic sulfamide with mammalian isoforms I-XV
Summary for 3MNU
Entry DOI | 10.2210/pdb3mnu/pdb |
Related | 1CA2 |
Descriptor | Carbonic anhydrase 2, ZINC ION, MERCURIBENZOIC ACID, ... (7 entities in total) |
Functional Keywords | protein-inhibitor complex, lyase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P00918 |
Total number of polymer chains | 1 |
Total formula weight | 30031.30 |
Authors | Di Fiore, A.,De Simone, G. (deposition date: 2010-04-22, release date: 2010-06-16, Last modification date: 2023-09-06) |
Primary citation | Di Fiore, A.,Monti, S.M.,Innocenti, A.,Winum, J.Y.,De Simone, G.,Supuran, C.T. Carbonic anhydrase inhibitors: crystallographic and solution binding studies for the interaction of a boron-containing aromatic sulfamide with mammalian isoforms I-XV. Bioorg.Med.Chem.Lett., 20:3601-3605, 2010 Cited by PubMed: 20472429DOI: 10.1016/j.bmcl.2010.04.114 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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