3LT4
Enoyl-ACP Reductase from Plasmodium falciparum (PfENR) in complex with triclosan variant PB4
Summary for 3LT4
Entry DOI | 10.2210/pdb3lt4/pdb |
Related | 1UH5 1V35 1ZSN 1ZXL 2OL4 2OOS 3LSY 3LT0 3LT1 3LT2 |
Descriptor | Enoyl-ACP reductase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, 2-(2-amino-4-chlorophenoxy)-5-chlorophenol, ... (4 entities in total) |
Functional Keywords | triclosan, triclosan variant, enoyl-acp reductase, oxidoreductase, p.falciparum |
Biological source | Plasmodium falciparum |
Total number of polymer chains | 2 |
Total formula weight | 76355.44 |
Authors | Maity, K.,Bhargav, S.P.,Surolia, N.,Surolia, A.,Suguna, K. (deposition date: 2010-02-15, release date: 2010-06-16, Last modification date: 2023-11-01) |
Primary citation | Maity, K.,Bhargav, S.P.,Sankaran, B.,Surolia, N.,Surolia, A.,Suguna, K. X-ray crystallographic analysis of the complexes of enoyl acyl carrier protein reductase of Plasmodium falciparum with triclosan variants to elucidate the importance of different functional groups in enzyme inhibition Iubmb Life, 62:467-476, 2010 Cited by PubMed: 20503440DOI: 10.1002/iub.327 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
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