3LRS
Structure of PG16, an antibody with broad and potent neutralization of HIV-1
Summary for 3LRS
Entry DOI | 10.2210/pdb3lrs/pdb |
Descriptor | PG-16 Heavy Chain Fab, PG-16 Light Chain Fab, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total) |
Functional Keywords | neutralizing antibodies, long cdrh3, hiv-1, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 8 |
Total formula weight | 193219.04 |
Authors | Pancera, M.,Kwong, P.D. (deposition date: 2010-02-11, release date: 2010-06-09, Last modification date: 2023-09-06) |
Primary citation | Pancera, M.,McLellan, J.S.,Wu, X.,Zhu, J.,Changela, A.,Schmidt, S.D.,Yang, Y.,Zhou, T.,Phogat, S.,Mascola, J.R.,Kwong, P.D. Crystal structure of PG16 and chimeric dissection with somatically related PG9: structure-function analysis of two quaternary-specific antibodies that effectively neutralize HIV-1. J.Virol., 84:8098-8110, 2010 Cited by PubMed: 20538861DOI: 10.1128/JVI.00966-10 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.37 Å) |
Structure validation
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