3LQC

X-ray crystal structure of oxidized XRCC1 bound to DNA pol beta Palm thumb domain

Summary for 3LQC

Entry DOI	10.2210/pdb3lqc/pdb
Related	3K75 3K77
Descriptor	DNA repair protein XRCC1, DNA polymerase beta, SODIUM ION, ... (5 entities in total)
Functional Keywords	allosteric disulfide, scaffolding protein, dna repair, dna damage, nucleus, phosphoprotein, polymorphism, dna replication, dna synthesis, dna-binding, dna-directed dna polymerase, lyase, magnesium, metal-binding, nucleotidyltransferase, sodium, transferase, dna-binding protein, dna binding protein
Biological source	Homo sapiens (human) More
Cellular location	Nucleus: P18887 P06766
Total number of polymer chains	2
Total formula weight	44667.04
Authors	Cuneo, M.J.,Krahn, J.M.,London, R.E. (deposition date: 2010-02-09, release date: 2010-04-28, Last modification date: 2023-09-06)
Primary citation	Cuneo, M.J.,London, R.E. Oxidation state of the XRCC1 N-terminal domain regulates DNA polymerase beta binding affinity. Proc.Natl.Acad.Sci.USA, 107:6805-6810, 2010 Cited by PubMed: 20351257 DOI: 10.1073/pnas.0914077107 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.349 Å)

Structure validation