3LQA

Crystal structure of clade C gp120 in complex with sCD4 and 21c Fab

Summary for 3LQA

• Entry DOI: 10.2210/pdb3lqa/pdb
• Related: 3LMJ
• Descriptor: T-cell surface glycoprotein CD4, Envelope glycoprotein gp160, Heavy chain of anti HIV Fab from human 21c antibody, ... (5 entities in total)
• Functional Keywords: complex, poly reactivity, immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 4
• Total formula weight: 106586.60

Authors

Diskin, R.,Marcovecchio, P.M.,Bjorkman, P.J. (deposition date: 2010-02-08, release date: 2010-04-07, Last modification date: 2021-10-13)

• Primary citation: Diskin, R.,Marcovecchio, P.M.,Bjorkman, P.J.; Structure of a clade C HIV-1 gp120 bound to CD4 and CD4-induced antibody reveals anti-CD4 polyreactivity.; Nat.Struct.Mol.Biol., 17:608-613, 2010; PubMed: 20357769; DOI: 10.1038/nsmb.1796

Experimental method

X-RAY DIFFRACTION (3.4 Å)