3LEO
Structure of human Leukotriene C4 synthase mutant R31Q in complex with glutathione
Summary for 3LEO
Entry DOI | 10.2210/pdb3leo/pdb |
Related | 2UUH |
Descriptor | Leukotriene C4 synthase, PALMITOLEIC ACID, PALMITIC ACID, ... (9 entities in total) |
Functional Keywords | leukotriene c4 synthase, endoplasmic reticulum, leukotriene biosynthesis, lyase, membrane, nucleus, transmembrane |
Biological source | Homo sapiens |
Cellular location | Nucleus outer membrane; Multi-pass membrane protein: Q16873 |
Total number of polymer chains | 1 |
Total formula weight | 20518.19 |
Authors | Niegowski, D.,Martinez-Molina, D.,Rinaldo-Matthis, A.,Nordlund, P.,Haeggstrom, J. (deposition date: 2010-01-15, release date: 2010-10-27, Last modification date: 2023-09-06) |
Primary citation | Rinaldo-Matthis, A.,Wetterholm, A.,Martinez Molina, D.,Holm, J.,Niegowski, D.,Ohlson, E.,Nordlund, P.,Morgenstern, R.,Haeggstrom, J.Z. Arginine 104 is a key catalytic residue in leukotriene C4 synthase. J.Biol.Chem., 285:40771-40776, 2010 Cited by PubMed: 20980252DOI: 10.1074/jbc.M110.105940 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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