3LEO
Structure of human Leukotriene C4 synthase mutant R31Q in complex with glutathione
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Leukotriene C4 synthase | polymer | 155 | 17251.3 | 1 | UniProt (Q16873) Pfam (PF01124) | Homo sapiens | LTC4 synthase, Leukotriene-C(4) synthase |
| 2 | B, P (A) | PALMITOLEIC ACID | non-polymer | 254.4 | 2 | Chemie (PAM) | |||
| 3 | C, D, E, G, H... (A) | PALMITIC ACID | non-polymer | 256.4 | 6 | Chemie (PLM) | |||
| 4 | F, J (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 5 | K, L (A) | NICKEL (II) ION | non-polymer | 58.7 | 2 | Chemie (NI) | |||
| 6 | M (A) | GLUTATHIONE | non-polymer | 307.3 | 1 | Chemie (GSH) | |||
| 7 | N (A) | DODECYL-BETA-D-MALTOSIDE | non-polymer | 510.6 | 1 | Chemie (LMT) | |||
| 8 | O (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 9 | Q (A) | water | water | 18.0 | 76 | Chemie (HOH) |
Sequence modifications
A: 2 - 150 (UniProt: Q16873)
| PDB | External Database | Details |
|---|---|---|
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
| His 1 | - | expression tag |
| Gln 31 | Arg 31 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 17251.3 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 3266.9 | |
| All* | Total formula weight | 20518.2 |
