3LAP

The Structure of the Intermediate Complex of the Arginine Repressor from Mycobacterium tuberculosis Bound to its DNA Operator and L-canavanine.

Summary for 3LAP

• Entry DOI: 10.2210/pdb3lap/pdb
• Related: 2zfz 3bue 3cag 3ere 3fhz 3laj
• Descriptor: Arginine repressor, 5'-D(*TP*TP*GP*CP*AP*TP*AP*AP*CP*GP*AP*TP*GP*CP*AP*A)-3', 5'-D(*TP*TP*GP*CP*AP*TP*CP*GP*TP*TP*AP*TP*GP*CP*AP*A)-3', ... (6 entities in total)
• Functional Keywords: mycobacterium tuberculosis, arginine repressor, dna binding, argr-dna-canavanine ternary complex, structural genomics, tb structural genomics consortium, tbsgc, mycobacterium tuberculosis structural proteomics project, xmtb, amino-acid biosynthesis, arginine biosynthesis, cytoplasm, dna-binding, repressor, transcription, transcription regulation, transcription regulator, transcription regulator-dna complex, transcription regulator/dna
• Biological source: Mycobacterium tuberculosis
• Cellular location: Cytoplasm (Probable): P0A4Y8
• Total number of polymer chains: 12
• Total formula weight: 135408.58

Authors

Cherney, L.T.,Cherney, M.M.,Garen, C.R.,James, M.N.G.,TB Structural Genomics Consortium (TBSGC) (deposition date: 2010-01-06, release date: 2010-05-05, Last modification date: 2023-11-15)

• Primary citation: Cherney, L.T.,Cherney, M.M.,Garen, C.R.,James, M.N.; crystal structure of the intermediate complex of the arginine repressor from Mycobacterium tuberculosis bound with its DNA operator reveals detailed mechanism of arginine repression.; J.Mol.Biol., 399:240-254, 2010; PubMed: 20382162; DOI: 10.1016/j.jmb.2010.03.065

Experimental method

X-RAY DIFFRACTION (2.15 Å)