3KIG

Mutant carbonic anhydrase II in complex with an azide and an alkyne

Summary for 3KIG

• Entry DOI: 10.2210/pdb3kig/pdb
• Related: 1Z9Y
• Descriptor: Carbonic anhydrase 2, ZINC ION, 2-azido-N-(2-sulfanylethyl)ethanamide, ... (5 entities in total)
• Functional Keywords: 10 stranded, twisted beta-sheets, lyase, disease mutation, metal-binding
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 30338.60

Authors

Schulze-Wischeler, J.,Niehage, N.U.,Heine, A.,Klebe, G. (deposition date: 2009-11-02, release date: 2010-11-17, Last modification date: 2024-02-21)

• Primary citation: Schulze Wischeler, J.,Sun, D.,Sandner, N.U.,Linne, U.,Heine, A.,Koert, U.,Klebe, G.; Stereo- and Regioselective Azide/Alkyne Cycloadditions in Carbonic Anhydrase II via Tethering, Monitored by Crystallography and Mass Spectrometry.; Chemistry, 17:5842-5851, 2011; PubMed: 21506176; DOI: 10.1002/chem.201002437

Experimental method

X-RAY DIFFRACTION (1.39 Å)