3KEM

Crystal structure of IspH:IPP complex

Summary for 3KEM

Entry DOI	10.2210/pdb3kem/pdb
Related	3DNF 3F7T 3KE8 3KE9 3KEF 3KEL
Descriptor	4-hydroxy-3-methylbut-2-enyl diphosphate reductase, 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, FE3-S4 CLUSTER, ... (4 entities in total)
Functional Keywords	isph, lytb, iron sulfure protein, malaria, tuberculosis, non-mevalonic acid pathway, iron, iron-sulfur, isoprene biosynthesis, metal-binding, nadp, oxidoreductase
Biological source	Escherichia coli
Total number of polymer chains	2
Total formula weight	73241.58
Authors	Groll, M.,Graewert, T.,Span, I.,Eisenreich, W.,Bacher, A. (deposition date: 2009-10-26, release date: 2010-01-12, Last modification date: 2023-11-01)
Primary citation	Grawert, T.,Span, I.,Eisenreich, W.,Rohdich, F.,Eppinger, J.,Bacher, A.,Groll, M. Probing the reaction mechanism of IspH protein by x-ray structure analysis. Proc.Natl.Acad.Sci.USA, 107:1077-1081, 2010 Cited by PubMed: 20080550 DOI: 10.1073/pnas.0913045107 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation