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3KEF

Crystal structure of IspH:DMAPP-complex

Summary for 3KEF
Entry DOI10.2210/pdb3kef/pdb
Related3DNF 3F7T 3KE8 3KE9 3KEL 3KEM
Descriptor4-hydroxy-3-methylbut-2-enyl diphosphate reductase, FE3-S4 CLUSTER, DIMETHYLALLYL DIPHOSPHATE, ... (4 entities in total)
Functional Keywordsisph, lytb, non-mevalonic acid pathway, drug design, tuberculosis, malaria, iron, iron-sulfur, isoprene biosynthesis, metal-binding, nadp, oxidoreductase
Biological sourceEscherichia coli
Total number of polymer chains2
Total formula weight73241.58
Authors
Groll, M.,Graewert, T.,Span, I.,Eisenreich, W.,Bacher, A. (deposition date: 2009-10-26, release date: 2010-01-12, Last modification date: 2023-11-01)
Primary citationGrawert, T.,Span, I.,Eisenreich, W.,Rohdich, F.,Eppinger, J.,Bacher, A.,Groll, M.
Probing the reaction mechanism of IspH protein by x-ray structure analysis.
Proc.Natl.Acad.Sci.USA, 107:1077-1081, 2010
Cited by
PubMed: 20080550
DOI: 10.1073/pnas.0913045107
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.7 Å)
Structure validation

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