3K9F
Detailed structural insight into the quinolone-DNA cleavage complex of type IIA topoisomerases
Summary for 3K9F
Entry DOI | 10.2210/pdb3k9f/pdb |
Related | 2NOV 3FOE 3FOF |
Descriptor | DNA topoisomerase 4 subunit A, DNA topoisomerase 4 subunit B, DNA (5'-D(*AP*CP*CP*AP*AP*GP*GP*T*CP*AP*TP*GP*AP*AP*T)-3'), ... (9 entities in total) |
Functional Keywords | quinolone, topoisomerase, dna, protein-dna cleavage complex, streptococcus pneumoniae, levofloxacin, cell membrane, dna-binding, isomerase, membrane, atp-binding, nucleotide-binding, isomerase-dna complex, isomerase/dna |
Biological source | Streptococcus pneumoniae More |
Cellular location | Cell membrane; Peripheral membrane protein (By similarity): P72525 |
Total number of polymer chains | 8 |
Total formula weight | 195339.21 |
Authors | Laponogov, I.,Pan, X.-S.,Veselkov, D.A.,Fisher, L.M.,Sanderson, M.R. (deposition date: 2009-10-15, release date: 2009-10-27, Last modification date: 2023-11-01) |
Primary citation | Laponogov, I.,Pan, X.-S.,Veselkov, D.A.,McAuley, K.E.,Fisher, L.M.,Sanderson, M.R. Structural Basis of Gate-DNA Breakage and Resealing by Type II Topoisomerases Plos One, 5:e11338-e11338, 2010 Cited by PubMed: 20596531DOI: 10.1371/journal.pone.0011338 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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