3K8D
Crystal structure of E. coli lipopolysaccharide specific CMP-KDO synthetase in complex with CTP and 2-deoxy-Kdo
Summary for 3K8D
Entry DOI | 10.2210/pdb3k8d/pdb |
Related | 3K8E |
Descriptor | 3-deoxy-manno-octulosonate cytidylyltransferase, MAGNESIUM ION, 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid, ... (5 entities in total) |
Functional Keywords | kdsb synthetase kdo complex, lipopolysaccharide biosynthesis, magnesium, nucleotidyltransferase, transferase |
Biological source | Escherichia coli |
Cellular location | Cytoplasm (Potential): P04951 |
Total number of polymer chains | 4 |
Total formula weight | 120808.12 |
Authors | Heyes, D.J.,Levy, C.W.,Lafite, P.,Scrutton, N.S.,Leys, D. (deposition date: 2009-10-14, release date: 2009-11-10, Last modification date: 2023-11-01) |
Primary citation | Heyes, D.J.,Levy, C.,Lafite, P.,Roberts, I.S.,Goldrick, M.,Stachulski, A.V.,Rossington, S.B.,Stanford, D.,Rigby, S.E.J.,Scrutton, N.S.,Leys, D. Structure-based mechanism of CMP-2-keto-3-deoxymanno-octulonic acid synthetase: convergent evolution of a sugar-activating enzyme with DNA/RNA polymerases J.Biol.Chem., 284:35514-35523, 2009 Cited by PubMed: 19815542DOI: 10.1074/jbc.M109.056630 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
Download full validation report