3JQZ

Crystal Structure of Human serum albumin complexed with Lidocaine

Summary for 3JQZ

Entry DOI	10.2210/pdb3jqz/pdb
Related	1AO6 1BM0 1E7E 2BXC 2BXF 2BXN
Descriptor	Serum albumin, 2-(diethylamino)-N-(2,6-dimethylphenyl)ethanamide (2 entities in total)
Functional Keywords	transport protein, albumin, carrier protein, drug-binding, lidocaine, alternative splicing, cleavage on pair of basic residues, copper, disease mutation, disulfide bond, glycation, glycoprotein, lipid-binding, metal-binding, phosphoprotein, polymorphism, secreted
Biological source	Homo sapiens (human)
Cellular location	Secreted: P02768
Total number of polymer chains	2
Total formula weight	133376.77
Authors	Hein, K.L.,Kragh-Hansen, U.,Morth, J.P.,Nissen, P. (deposition date: 2009-09-08, release date: 2010-04-21, Last modification date: 2023-11-01)
Primary citation	Hein, K.L.,Kragh-Hansen, U.,Morth, J.P.,Jeppesen, M.D.,Otzen, D.,Moller, J.V.,Nissen, P. Crystallographic analysis reveals a unique lidocaine binding site on human serum albumin. J.Struct.Biol., 2010 Cited by PubMed: 20347991 DOI: 10.1016/j.jsb.2010.03.014 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.3 Å)

Structure validation