3J2T

An improved model of the human apoptosome

Replaces:  3IZAReplaces:  3IYT

Summary for 3J2T

• Entry DOI: 10.2210/pdb3j2t/pdb
• EMDB information: 5186
• Descriptor: Apoptotic protease-activating factor 1, Cytochrome c, ADENOSINE-5'-TRIPHOSPHATE, ... (4 entities in total)
• Functional Keywords: apoptosis protease activating factor-1, apaf-1, cytochrome c, apoptosis
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 14
• Total formula weight: 1097704.10

Authors

Yuan, S.,Topf, M.,Akey, C.W. (deposition date: 2012-12-23, release date: 2013-04-10, Last modification date: 2018-07-18)

• Primary citation: Yuan, S.,Topf, M.,Reubold, T.F.,Eschenburg, S.,Akey, C.W.; Changes in apaf-1 conformation that drive apoptosome assembly.; Biochemistry, 52:2319-2327, 2013; PubMed: 23521171; DOI: 10.1021/bi301721g

Experimental method

ELECTRON MICROSCOPY (9.5 Å)