3IXY

The pseudo-atomic structure of dengue immature virus in complex with Fab fragments of the anti-fusion loop antibody E53

Summary for 3IXY

Entry DOI	10.2210/pdb3ixy/pdb
EMDB information	5102
Descriptor	Envelope protein E, Peptide pr, E53 Fab Fragment (chain H), ... (4 entities in total)
Functional Keywords	dengue virus, denv, immature, fusion loop, fab, e53, atp-binding, envelope protein, helicase, hydrolase, membrane, nucleotide-binding, rna replication, transmembrane, virion, capsid protein, cleavage on pair of basic residues, core protein, endoplasmic reticulum, glycoprotein, secreted, virus
Biological source	Dengue virus 2 More
Total number of polymer chains	10
Total formula weight	253935.05
Authors	Cherrier, M.V.,Kaufmann, B.,Nybakken, G.E.,Lok, S.M.,Warren, J.T.,Nelson, C.A.,Kostyuchenko, V.A.,Holdaway, H.A.,Chipman, P.R.,Kuhn, R.J.,Diamond, M.S.,Rossmann, M.G.,Fremont, D.H. (deposition date: 2009-02-26, release date: 2009-10-27, Last modification date: 2024-02-21)
Primary citation	Cherrier, M.V.,Kaufmann, B.,Nybakken, G.E.,Lok, S.M.,Warren, J.T.,Chen, B.R.,Nelson, C.A.,Kostyuchenko, V.A.,Holdaway, H.A.,Chipman, P.R.,Kuhn, R.J.,Diamond, M.S.,Rossmann, M.G.,Fremont, D.H. Structural basis for the preferential recognition of immature flaviviruses by a fusion-loop antibody Embo J., 28:3269-3276, 2009 Cited by PubMed: 19713934 DOI: 10.1038/emboj.2009.245 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (23 Å)

Structure validation