3ISG
Structure of the class D beta-lactamase OXA-1 in complex with doripenem
Summary for 3ISG
Entry DOI | 10.2210/pdb3isg/pdb |
Descriptor | Beta-lactamase OXA-1, (2S,3R,4S)-2-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-3-methyl-4-({(3S,5S)-5-[(sulfamoylamino)methyl]pyrrolidin-3-yl}sulfanyl)-3,4-dihydro-2H-pyrrole-5-carboxylic acid, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (4 entities in total) |
Functional Keywords | hydrolase, lysine carboxylation, antibiotic resistance |
Biological source | Escherichia coli |
Total number of polymer chains | 2 |
Total formula weight | 57370.88 |
Authors | Powers, R.A. (deposition date: 2009-08-25, release date: 2009-12-01, Last modification date: 2023-11-22) |
Primary citation | Schneider, K.D.,Karpen, M.E.,Bonomo, R.A.,Leonard, D.A.,Powers, R.A. The 1.4 A crystal structure of the class D beta-lactamase OXA-1 complexed with doripenem. Biochemistry, 48:11840-11847, 2009 Cited by PubMed: 19919101DOI: 10.1021/bi901690r PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.4 Å) |
Structure validation
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