3IM6

Crystal structure of mouse Ryanodine Receptor 2 mutant V186M

Summary for 3IM6

Entry DOI	10.2210/pdb3im6/pdb
Related	3ILA 3IM5 3IM7
Descriptor	Cardiac Ca2+ release channel, SULFATE ION (3 entities in total)
Functional Keywords	ryanodine receptor 2, calcium release channel, ion channel, arrhythmia, cpvt, arvd2, arvc2, disease mutation, ion transport, ionic channel, transmembrane, transport, signaling protein
Biological source	Mus musculus (mouse)
Total number of polymer chains	1
Total formula weight	24295.33
Authors	Van Petegem, F.,Lobo, P.A. (deposition date: 2009-08-09, release date: 2009-11-17, Last modification date: 2023-09-06)
Primary citation	Lobo, P.A.,Van Petegem, F. Crystal structures of the N-terminal domains of cardiac and skeletal muscle ryanodine receptors: insights into disease mutations. Structure, 17:1505-1514, 2009 Cited by PubMed: 19913485 DOI: 10.1016/j.str.2009.08.016 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation