3I5R

PI3K SH3 domain in complex with a peptide ligand

Summary for 3I5R

• Entry DOI: 10.2210/pdb3i5r/pdb
• Related: 3I5S
• Descriptor: Phosphatidylinositol 3-kinase regulatory subunit alpha, Peptide ligand (3 entities in total)
• Functional Keywords: sh3 domain, peptide complex, alternative splicing, disease mutation, host-virus interaction, phosphoprotein, polymorphism, sh2 domain, ubl conjugation, protein binding
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 10780.98

Authors

Batra-Safferling, R.,Granzin, J.,Modder, S.,Hoffmann, S.,Willbold, D. (deposition date: 2009-07-06, release date: 2010-03-02, Last modification date: 2023-09-06)

• Primary citation: Batra-Safferling, R.,Granzin, J.,Modder, S.,Hoffmann, S.,Willbold, D.; Structural studies of the phosphatidylinositol 3-kinase (PI3K) SH3 domain in complex with a peptide ligand: role of the anchor residue in ligand binding.; Biol.Chem., 391:33-42, 2010; PubMed: 19919182; DOI: 10.1515/BC.2010.003

Experimental method

X-RAY DIFFRACTION (1.7 Å)