3HPR
Crystal structure of V148G adenylate kinase from E. coli, in complex with Ap5A
Summary for 3HPR
| Entry DOI | 10.2210/pdb3hpr/pdb |
| Related | 3HPQ |
| Descriptor | Adenylate kinase, BIS(ADENOSINE)-5'-PENTAPHOSPHATE (3 entities in total) |
| Functional Keywords | enzyme inhibitor complex, atp-binding, kinase, nucleotide biosynthesis, nucleotide-binding, transferase |
| Biological source | Escherichia coli |
| Cellular location | Cytoplasm: P69441 |
| Total number of polymer chains | 2 |
| Total formula weight | 48988.63 |
| Authors | Hilser, V.J.,Travis, T.P.,Bolen, D.W. (deposition date: 2009-06-04, release date: 2009-11-03, Last modification date: 2023-09-06) |
| Primary citation | Schrank, T.P.,Bolen, D.W.,Hilser, V.J. Rational modulation of conformational fluctuations in adenylate kinase reveals a local unfolding mechanism for allostery and functional adaptation in proteins. Proc.Natl.Acad.Sci.USA, 106:16984-16989, 2009 Cited by PubMed: 19805185DOI: 10.1073/pnas.0906510106 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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