3HOM

Crystal structure of oxidized A66C mutant of Human acidic fibroblast growth factor

Summary for 3HOM

Entry DOI	10.2210/pdb3hom/pdb
Related	1JQZ 3FJK
Descriptor	Acidic fibroblast growth factor, FORMIC ACID, SULFATE ION, ... (4 entities in total)
Functional Keywords	beta-trefoil, acetylation, alternative splicing, angiogenesis, developmental protein, differentiation, growth factor, heparin-binding, mitogen, polymorphism, hormone
Biological source	Homo sapiens (human)
Cellular location	Secreted: P05230
Total number of polymer chains	2
Total formula weight	33625.74
Authors	Blaber, M.,Lee, J. (deposition date: 2009-06-02, release date: 2009-10-06, Last modification date: 2023-09-06)
Primary citation	Lee, J.,Blaber, M. Structural basis of conserved cysteine in the fibroblast growth factor family: evidence for a vestigial half-cystine. J.Mol.Biol., 393:128-139, 2009 Cited by PubMed: 19683004 DOI: 10.1016/j.jmb.2009.08.007 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation